| 摘要 |
PROBLEM TO BE SOLVED: To obtain a new compound substituted with a cyclic amine at a para position and useful as an intermediate for synthesizing a photoinitiator for photopolymerization of an ethylenically unsaturated compound. SOLUTION: This new compound is a compound of formula I (R<1> and R<2> together become O, S, or a 3-20C alkylene, which may be discontinued by N(R4 ); R3 is a 2-20C alkyl; R4 is H, a 1-3C alkyl, a 3-5C alkenyl, phenyl, etc.; etc.), e.g. 1-(4-morpholinophenyl)butan-1-one. A compound of formula I is obtained by subjecting a p-halophenyl alkyl ketone of formula II (X is a halogen) to aminolysis using a cyclic amine of formula III in water at a temperature of at least 130 deg.C. The compound of formula III is used in an amount of 2.5-12mol equivalent and further water is used in an amount of 1-100mol equivalent, each based on the compound of formula II. Examples of a compound of formula II include 1-(4-bromophenyl)butan-1-one, and examples of a cyclic amine of formula III include morpholine. |
