发明名称 |
Marker for individuals susceptible to alcoholism |
摘要 |
The present invention relates to methods for diagnosis of susceptibility to alcoholism or the pathological effects of alcoholism based on detection of a genetic marker in an individual. The present invention is directed generally to methods and associated compositions and kits for detecting the presence of arylsulfatase A (ASA) pseudodeficiency (PD) mutations in humans. Detection of these mutations has been surprisingly found to be a strong indicator for susceptibility to alcoholism and/or susceptibility to alcohol's pathological effects, as well as an important marker in evaluating the likelihood of metachromatic leukodystrophy (MLD).
|
申请公布号 |
US5736325(A) |
申请公布日期 |
1998.04.07 |
申请号 |
US19940299187 |
申请日期 |
1994.08.31 |
申请人 |
ALGENE LLC |
发明人 |
MANOWITZ, PAUL;PORETZ, RONALD D.;PARK, DAVID;RICKETTS, MICHAEL |
分类号 |
C07K16/40;C12N9/16;C12Q1/68;G01N33/573;(IPC1-7):C12Q1/68;C07H21/04;C12N15/00 |
主分类号 |
C07K16/40 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|