| 发明名称 |
HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR 2 |
| 摘要 |
<p>Disclosed is a human VEGF2 polypeptide and DNA (RNA) encoding such VEGF2 polypeptides. Also provided is a procedure for producing such polypeptide by recombinant techniques and antibodies and antagonist against such polypeptide. Also disclosed is a method of using such polypeptide for stimulating wound healing and for vascular tissue repair. Also provided are methods of using the antagonists to inhibit tumor growth, inflammation and to treat diabetic retinopathy, rheumatoid arthritis and psoriasis. Diagnostic methods for detecting mutations in the VEGF2 coding sequence and alterations in the concentration of VEGF2 protein in a sample derived from a host are also disclosed.</p> |
| 申请公布号 |
MX9709243(A) |
申请公布日期 |
1998.03.31 |
| 申请号 |
MX19970009243 |
申请日期 |
1996.06.06 |
| 申请人 |
HUMAN GENOME SCIENCES, INC. |
发明人 |
CRAIG A. ROSEN;JING-SHAN HU;LIANG CAO |
| 分类号 |
C12N15/09;A61K31/00;A61K38/00;A61K38/22;A61K38/27;A61K38/55;A61K39/00;A61K39/395;A61K48/00;A61K49/00;A61P3/10;A61P9/00;A61P9/14;A61P17/00;A61P17/02;A61P17/06;A61P27/00;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07H21/04;C07K14/475;C07K14/485;C07K14/515;C07K14/52;C07K16/24;C12N1/19;C12N1/21;C12N5/10;C12N15/18;C12P21/02;C12P21/08;C12Q1/68;G01N33/53;(IPC1-7):C12N15/12;C07K14/49;C07K14/50;C07K14/65;C12N15/19 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
