发明名称 8-substituted xanthine derivatives and method of use thereof
摘要 A method for the treatment of cerebrovascular disorders and/or disorders associated with cerebral senility and/or other disorders which method comprises the administration of an effective, non-toxic amount of a compound of formula (I): <IMAGE> (I) or if appropriate a pharmaceutically acceptable salt thereof, wherein R1 and R2 each independently represent alkyl or a moiety of formula (a):-(CH2)m-A(a)wherein m represents zero or an integer 1, 2 or 3; A represents a substituted or unsubstituted cyclic hydrocarbon radical; and R3 represents a halogen atom, a nitro group, or a group -NR4R5 wherein R4 and R5 each independently represents hydrogen, alkyl or alkylcarbonyl or R4 and R5 together with the nitrogen to which they are attached forming an optionally substituted, heterocyclic group; certain novel compounds falling within formula (I) and compositions comprising such compounds.
申请公布号 US5734051(A) 申请公布日期 1998.03.31
申请号 US19950477157 申请日期 1995.06.07
申请人 BEECHAM GROUP 发明人 SPICER, BARBARA ANN;SMITH, HARRY;MASCHLER, HARALD
分类号 C07D473/04;A61K31/52;A61K31/522;A61K31/535;A61K31/5377;A61P9/00;A61P9/08;A61P9/10;A61P11/00;A61P25/00;A61P25/28;A61P37/08;C07D239/545;C07D473/06;C07D473/08;(IPC1-7):C07D473/06 主分类号 C07D473/04
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