发明名称 |
Compositions and methods for specifically targeting tumors |
摘要 |
The present invention provides a method and compositions for specifically delivering an effector molecule to a tumor cell. The method involves providing a chimeric molecule comprising an effector molecule attached to a targeting molecule that specifically binds an IL-13 receptor and contacting a tumor cell with the chimeric molecule in the presence of an interleukin-4 receptor (IL-4R) blocker. |
申请公布号 |
AU4164097(A) |
申请公布日期 |
1998.03.19 |
申请号 |
AU19970041640 |
申请日期 |
1997.08.27 |
申请人 |
THE PENN STATE RESEARCH FOUNDATION |
发明人 |
WALDEMAR DEBINSKI;RAJ K PURI |
分类号 |
C12N15/09;A61K38/00;A61K38/20;A61K39/395;A61K45/00;A61K47/48;A61K51/00;A61K51/08;A61P35/00;C07K14/21;C07K14/54;C07K14/715;C07K16/28;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/24 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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