发明名称 |
SUBSTITUTED BENZOCYCLOHEPTAPYRIDINE DERIVATIVES USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE |
摘要 |
Novel compounds of formula (1.0) are disclosed. Compounds of formula (1.0) are represented by the compounds of formulas (1.4) or (1.5) wherein R1, R3 and R4 are each independently selected from halo. W represents a group selected from (a), (b), (c) or (d). Also disclosed are methods of inhibiting farnesyl protein transferase and the growth of abnormal cells, such as tumor cells.
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申请公布号 |
CA2264513(A1) |
申请公布日期 |
1998.03.19 |
申请号 |
CA19972264513 |
申请日期 |
1997.09.11 |
申请人 |
SCHERING CORPORATION |
发明人 |
TAVERAS, ARTHUR G.;NJOROGE, F. GEORGE |
分类号 |
A61K31/4545;A61K31/496;A61K31/5377;A61P35/00;C07D401/14;C07D405/14;(IPC1-7):C07D401/14;C07H5/06;A61K31/435 |
主分类号 |
A61K31/4545 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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