| 发明名称 |
Polymerase delta mutations in colorectal tumors with replication errors |
| 摘要 |
The human pol delta gene, responsible for a replication error phenotype in some colorectal tumors, can be used for diagnostic and therapeutic purposes. It can be used to demonstrate the existence of germline or somatic mutations in replication error (RER+) tumor cells.
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| 申请公布号 |
US5728523(A) |
申请公布日期 |
1998.03.17 |
| 申请号 |
US19940366577 |
申请日期 |
1994.12.30 |
| 申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
VOGELSTEIN, BERT;KINZLER, KENNETH W. |
| 分类号 |
A01K67/027;A61K38/00;A61K45/00;A61K48/00;A61P35/00;C12N9/12;C12N15/09;C12N15/54;C12Q1/02;(IPC1-7):C12Q1/68;C12P19/34;C07H21/02;C07H21/04 |
主分类号 |
A01K67/027 |
| 代理机构 |
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