发明名称 |
CIS-ACTING REPRESSION SEQUENCES, CIS-ACTING ANTI-REPRESSION SEQUENCES VECTORS, METHODS OF PREPARATION AND USE |
摘要 |
Cis-acting repression sequences which are able to provide a cis-acting inhibitory effect on the expression of a gene when placed downstream of the gene in its untranslated message are dislcosed. Cis-acting anti-repression sequences which can relieve the cis-acting repression in the presence of the art gene product are also disclosed. These sequences correspond to a sufficient number of nucleotides from the HIV-I, HIV-2, STLV-3 or HTLV-IV genomes to provide the repression or anti-repression effects. The use of the sequences in vectors and systems to control the expression of a desired gene product is also described. . . . .
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申请公布号 |
CA1339733(C) |
申请公布日期 |
1998.03.17 |
申请号 |
CA19880567929 |
申请日期 |
1988.05.27 |
申请人 |
DANA FARBER CANCER INSTITUTE |
发明人 |
HASELTINE, WILLIAM A.;ROSEN, CRAIG A.;SODROSKI, JOSEPH G.;TERWILLIGER, ERNEST |
分类号 |
C12N15/09;C07K14/61;C12N15/00;C12N15/11;C12N15/85;C12R1/91;(IPC1-7):C12N15/85 |
主分类号 |
C12N15/09 |
代理机构 |
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主权项 |
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地址 |
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