| 摘要 |
PROBLEM TO BE SOLVED: To obtain the subject pharmaceutical preparation which has excellent antiallergic effect with low toxicity and can become a component of an antiallergic food product by using an extract of peels of mangosteen fruits with a polar solvent. SOLUTION: This pharmaceutical preparation contains an extract of fruit peels of mangosteen (Garcinia mangostana L.) as an active ingredient. From this extract, α-mangosteen whose R is methyl in the formula and γ-mangosteen whose R is H can be obtained. This extract is obtained by extracting the fracture or powder of fruit peels of mangosteen with a polar solvent, preferably methanol or ethanol. This extract can be expected to be utilized as a medicine for treatment of allergies, for example, mammalian poloinosis, hay fever, allergic rhinitis, asthma atopic dermatitis or conjunctivitis. In addition, this active ingredient can be formulated to food products to produce antiallergic food products. |
