摘要 |
<p>The present invention provides compositions and methods which either prevent cell clumps from forming, or removing clumps which have formed, in cell separating devices. The present compositions contain a nuclease, divalent cations, and chelating agents. Surprisingly, nuclease activity is not decreased in the presence of chelating agents. During cell separation procedures using the present composition, cell yield, purity, and viability are enhanced. Also, kits for use with automated cell separating devices using these compositions are provided.</p> |