发明名称 |
Gene therapy delivery system for targeting to endothelia |
摘要 |
A composition comprising biodegradable microspheres that act as carriers for the delivery of DNA to the endothelial cells of a vascular bed, wherein the microspheres carry a net negative charge and to which is adsorbed positively charged particles of a smaller size, wherein such positively charged particles comprise a conjugate of DNA and a cationic compacting agent. |
申请公布号 |
WO9801161(A3) |
申请公布日期 |
1998.03.12 |
申请号 |
WO1997GB01860 |
申请日期 |
1997.07.10 |
申请人 |
DANBIOSYST UK LIMITED;ILLUM, LISBETH |
发明人 |
ILLUM, LISBETH |
分类号 |
B82B1/00;A61K9/16;A61K9/51;A61K47/36;A61K47/48;A61K48/00;C12N15/88 |
主分类号 |
B82B1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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