CHROMENE-3-CARBOXYLATE DERIVATIVES

摘要

Compounds represented by general formula (I), pharmaceutically acceptable salts thereof, and hydrates of the same; and medicinal compositions such as endothelin receptor antagonists, remedies for peripheral circulatory insufficiency or macrophage foaming inhibitors containing these compounds. In said formula (I), R<1>, R<2>, R<3> and R<4> independently represent each hydrogen, optionally substituted alkyl, hydroxy, optionally substituted alkoxy, etc.; R<5> represents optionally substituted alkyl, optionally substituted aryl, optionally substituted heterocycle, etc.; R<6> represents hydrogen, optionally substituted alkyl, etc.; R<7> represents hydrogen, optionally substituted alkyl, optionally substituted alkoxy, optionally substituted aryl, optionally substituted heterocycle, etc.; A represents S or O; and the broken line means the presence or absence of a bond.