POXVIRUS-CANINE DISTEMPER VIRUS (CDV) RECOMBINANTS AND COMPOSITIONS AND METHODS EMPLOYING THE RECOMBINANTS

摘要

Attenuated recombinant viruses containing DNA coding for a canine distemper virus antigen, as well as methods and compositions employing the viruses, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The DNA can code for at least one of: canine distemper virus fusion protein and canine distemper virus hemagglutinin glycoprotein. The recombinant viruses and gene products therefrom are useful for eliciting protection against canine distemper virus.