发明名称 PORPHOCYANINE AND CNC-EXPANDED PORPHYRINS.
摘要 <p>Compounds of formula (1) and the metalated forms and salts thereof; wherein n is an integer of 1-4; and wherein each Pi is independently a pyrrole residue of formula (II), wherein each Ria and Rib is independently a noninterfering substituent, and wherein each Zi is independently a covalent bond; or is a meso bridging group of formula (III); or is an N-meso bridging group of formula (IV); or is a CC linkage of formula (V) or is a CNCCNC linkage of formula (VI), wherein each Ric, Rid, Rie, Rif and Rig is independently a noninterfering substituent; or is a CNC linkage of formula (VII), wherein at least one Zi is said CNC linkage, are disclosed. These compounds are useful in photodynamic therapy and diagnosis. The metalated forms when the metal is paramagnetic are useful as MRI contrast agents.</p>
申请公布号 MX9604956(A) 申请公布日期 1998.02.28
申请号 MX19960004956 申请日期 1995.04.26
申请人 QUADRA-LOGIC TECHNOLOGIES, INC. 发明人 ROSS W. BOYLE;HANG TANG;LILY XIE;TILAK WIJESEKERA;DAVID DOLPHIN
分类号 (IPC1-7):A61K31/40;A61K49/00;C07B59/00 主分类号 (IPC1-7):A61K31/40
代理机构 代理人
主权项
地址