Injectable therapy for control of muscle spasms and pain related to muscle spasms

摘要

A method for administration of botulinum toxin, includes the steps of (a) selecting at least one neuromuscular blocking agent having a duration of activity shorter than neuromuscular blocking activity of botulinum toxin; (b) selecting at least one muscle of a muscle group; (c) intramuscularly injecting the selected agent into the selected muscle; (d) observing muscle relaxation in both the selected muscle and other nonselected muscles in the muscle group to determine spill-over, muscle tone and balance; (e) repeating steps (b)-(d) until a final muscle selection is found; and (f) intramuscularly injecting botulinum toxin into the final muscle selection.