NEURAMINIC ACID COMPOUNDS

摘要

Constitution: Neuraminic acid compounds represented by general formula (1) or pharmacologically acceptable salts thereof, wherein R1 represents an optionally halogenated C1-C4 group; R2, R3 and R4 represent each independently hydrogen or C3-C25 aliphatic acyl; and W represents hydrogen or an ester residue, provided the case where R1 represents methyl and each of R2, R3, R4 and W represents hydrogen is excluded. Effect: These compounds are excellent in the sialidase inhibitory activity in vivo and so are useful as a remedy or preventive for influenza virus infections.