| 摘要 |
<p>Compounds of formula (I), either in their racemic or enantiomeric forms, wherein R is H or a C1-C20 alkyl chain, which may be interrupted by O, N, S, -CO-, -CH(OH)-, -CH(NH2)-, -CONH-, -NHCO-, -SO-, -SO2-, -SO2NH-, may be substituted by halogen atoms or -COOH groups or their ester or amide derivatives and which is interrupted or not or substituted or not by one or more cyclic R3 residues. R3 is a 5- or 6-membered optionally substituted carbocyclic or heterocyclic, saturated, unsaturated or aromatic cyclic unit, R1, R2 have the same meanings as R, independently from each other, except H, with the proviso that: when R1 and R2 are both C6H5-CH2-O-CH2-, R is different from either H or C6H5-CH2-O-CH2-; as well as the complexes of the compounds of formula (I) with metal ions and the salts thereof with physiologically acceptable organic bases. The compounds are used in the preparation of diagnostic imaging contrast agents and in particular of contrast agents exhibiting improved serum relaxivity.</p> |
