RECOMBINANT SWINEPOX VIRUS

摘要

This invention provides a recombinant swinepox virus comprising a foreign DNA inserted into a swinepox virus genome, wherein the foreign DNA is inserted into a) an AccI site within a region corresponding to a 3.2 Kb HindIII to BglII subfragment of the HindII M fragment and b) an EcoRI site within a region corresponding to a 3.2 Kb subfragment of the HindIII K fragment which contains both a HindIII and EcoRI site, of the swinepox virus genome and is capable of being expressed in a host cell into which the virus is introduced. The invention further provides vaccines and methods of immunization of the recombinant swinepox virus.