THERAPEUTIC MULTISPECIFIC COMPOUNDS COMPRISED OF ANTI-FC alpha RECEPTOR ANTIBODIES

摘要

Multispecific compounds comprising at least one binding determinant which binds to the Fcx-receptor on an effector cell. The other binding determinant(s) binds(s) to one or more antigens on a target cell, e.g., the Neu/Her-2 proto-oncogene product or the epidermal growth factor receptor on cancer cells, or to Candida antigens on infected cells. Examples are biospecific and trispecific antibodies. Therapeutic use of said multispecific compounds for treatment of cancers or pathogen infections.