发明名称 NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS
摘要 There are provided compounds of formula (I), wherein R1, R2, R3, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
申请公布号 CA2260190(A1) 申请公布日期 1998.01.15
申请号 CA19972260190 申请日期 1997.06.26
申请人 ASTRA AKTIEBOLAG 发明人 ANTONSSON, THOMAS
分类号 A61K31/155;A61K31/18;A61K31/216;A61K31/255;A61K31/27;A61K31/275;A61K31/381;A61K31/4164;A61K31/42;A61P7/02;C07C309/71;C07C309/73;C07C311/13;C07C311/21;C07C311/29;C07C323/60;C07D233/56;C07D233/84;C07D261/14;C07D261/16;C07D333/34;C07F9/53;(IPC1-7):C07C311/21;C07D261/10;C07D401/12;C07D403/12;C07D409/12;C07D413/12;C07C311/14;A61K31/33;C07C317/44;C07C323/56;A61K31/66;C07C309/72 主分类号 A61K31/155
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