发明名称 |
Production of proteins using 7B2 protein |
摘要 |
PCT No. PCT/EP92/02740 Sec. 371 Date Sep. 2, 1994 Sec. 102(e) Date Sep. 2, 1994 PCT Filed Nov. 27, 1992 PCT Pub. No. WO93/11248 PCT Pub. Date Jun. 10, 1993The invention lies in the field of genetic engineering and, in particular, is concerned with the use of 7B2 as chaperone in vivo or in vitro. The invention accordingly concerns a method for producing a desired protein in vivo with the aid of recombinant cells capable of expressing 7B2 and of expressing and secreting said desired protein. Another aspect is accordingly an in vitro method for the deaggregation or prevention of aggregation of protein by treating the protein with 7B2.
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申请公布号 |
US5708140(A) |
申请公布日期 |
1998.01.13 |
申请号 |
US19940244492 |
申请日期 |
1994.09.02 |
申请人 |
CIBA-GEIGY CORPORATION |
发明人 |
MARTENS, GERARDUS JULIANUS MARIA;CHAUDHURI, BHABATOSH;STEPHAN, CHRISTINE |
分类号 |
C07K14/435;C07K1/113;C07K14/47;C07K14/52;C07K14/575;C07K14/65;C07K14/665;C07K14/745;C12N1/19;C12N15/09;C12N15/67;C12N15/81;C12P21/02;C12R1/865;(IPC1-7):C07K1/00 |
主分类号 |
C07K14/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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