摘要 |
PROBLEM TO BE SOLVED: To solve the problems in labor hygiene and pollution and to improve wettability and durability by subjecting a coating film obtd. from an aq. soln. contg. an active hydrogen-contg. water-soluble polymer and blocked isocyanato group-contg. water-soluble urethane prepolymer to a heat treatment, thereby forming a surface layer as a hydrophilic water-insoluble coating film layer. SOLUTION: The surface layer of a medical appliance is formed of the hydrophilic water-insoluble coating film layer. The hydrohpilic water-insoluble coating film layer is formed by subjecting the coating film obtd. from the aq. soln. contg. the water-soluble polymer having the active hydrogen to react with the isocyanate group, for example, polyethylene glycol, and the water-soluble urethane prepolymer having the blocked isocyanato group, to the heat treatment. The amts. of both polymers to be used are determined according to the desired degree of crosslinking, the respective degrees of polymn., etc. Usually, about 0.5 to 30 pts.wt. (by solid component) water-soluble urethane prepolymer is used per about 100 pts.wt. water-soluble polymer. |