| 摘要 |
PROBLEM TO BE SOLVED: To obtain a preparation for external use for skin, comprising an extract of a specific myrsinaceous plant or 1,4-benzoquinones contained in the extract as an active ingredient and having preventing effects on aging, antiinflammatory and beautifying and whitening effects together. SOLUTION: This preparation for external use comprises an extract of Ardisia japonica Blume, Ardisia quinquegona Blume and Ardisia sieboldi Miq. or 1,4-benzoquinones contained in the extract as an active ingredient. The blending concentration of the extract in the preparation for external use is about 0.1-1μM expressed in terms of the 1,4-benzoquinones and about 0.001-10wt.% in a state of a crude extract of the plant. The active ingredient has good scavenging actions on active oxygen species and further antiinflammatory actions based on inhibiting actions on 5-lipoxygenases and beautifying and whitening actions based on inhibiting actions, etc., on tyrosinases. The preparation is effective in reducing and preventing aging diseases of the skin mainly caused by oxidative stress, dermatitis, pigmentation such as dermal stains, ephelides or nevus Ota, blackening, etc., due to sunburn. |
