发明名称 |
Transgenic animals expressing artificial epitope-tagged proteins |
摘要 |
DNA constructs are provided of epitope-tagged proteins or protein fragments which are conveniently purified with immunoaffinity chromatography such as epitope-tagged prion proteins (PrP). Transgenic animals expressing an epitope-tagged protein are provided, including transgenic animals expressing epitope-tagged PrP. Methods for distinguishing between the conformational shapes of a protein and a convenient method for isolating a tagged protein by immunoaffinity chromatographic methods are provided. |
申请公布号 |
AU3222197(A) |
申请公布日期 |
1998.01.05 |
申请号 |
AU19970032221 |
申请日期 |
1997.05.29 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, |
发明人 |
STANLEY B PRUSINER;GLENN C. TELLING;FRED E. COHEN;MICHAEL R SCOTT |
分类号 |
A01K67/027;A61K47/48;A61K49/00;C07K14/42;C07K14/47;C12N5/10;C12N15/09;C12N15/85 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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