发明名称 |
Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent |
摘要 |
A method and composition for the treatment of HIV and HBV infections in humans and other host animals is disclosed that includes the administration of an effective amount of a [5-carboxamido or 5-fluoro]-2',3'-dideoxy-2',3'-didehydro-pyrimidine nucleoside or a [5-carboxamido or 5-fluoro]-3'-modified-pyrimidine nucleoside, or a mixture or a pharmaceutically acceptable derivative thereof, including a 5' or N4 alkylated or acylated derivative, or a pharmaceutically acceptable salt thereof, in a pharmaceutically acceptable carrier.
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申请公布号 |
US5703058(A) |
申请公布日期 |
1997.12.30 |
申请号 |
US19950379276 |
申请日期 |
1995.01.27 |
申请人 |
EMORY UNIVERSITY |
发明人 |
SCHINAZI, RAYMOND F.;LIOTTA, DENNIS C. |
分类号 |
C07D239/34;A61K9/20;A61K31/505;A61K31/513;A61K31/522;A61K31/675;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7068;A61K31/7072;A61K38/21;A61K45/06;A61P31/12;A61P31/18;A61P31/20;A61P37/04;C07D239/38;C07D405/04;C07H19/06;(IPC1-7):A61K31/70;C07H19/04;C07H19/20;C07H19/09;C07H19/10 |
主分类号 |
C07D239/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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