发明名称 POTASSIUM SALTS OF N-PROPIONYL-4-HYDROXY-3-NITRO-L-PHENYLALANINE AND N-PROPIONYL-4-METOXY-3-NITRO-DL-PHENYLALANINE HAVING ANTITUMOUR ACTIVITY
摘要 This invention describes biologically active compounds, such as water-soluble N-propionil-4-hydroxy-3-nitro-L-phenylalanine and N-propionyl-4-methoxy-3-nitro-DL-phenylalanine potassium salts. The synthetic derivatives of amino acids are slightly toxic, but the experiments with mice have shown a high level of effect against cells affected by cancer. They slow down the growth of sarcoma 180, respectively by 94.5 and 89 per cent, and lengthen the time of living by up to 50 per cent.
申请公布号 LT97098(A) 申请公布日期 1997.12.29
申请号 LT19970000098 申请日期 1997.05.29
申请人 BIOCHEMIJOS INSTITUTAS 发明人 STRAUKAS,JUOZAPAS;SIMKEVICIENE,VITALIJA;JANKAUSKAS,RIMAS
分类号 A61K31/195;C07C229/34 主分类号 A61K31/195
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