METHOD OF SCREENING FOODS FOR NUTRACEUTICALS

摘要

The invention relates to an assay system for screening nutraceuticals, i.e., foods or food substances that occur naturally, or that are produced during processing which are capable of modulating in a subject the expression of one or more genes associated with a disease or undesirable condition. The effect of nutraceuticals on lysyl oxidase promoter activity is shown in the figure. The nutraceuticals identified by the screening assays can be incorporated into compositions which may be administered to a subject to treat or prevent a disease or undesirable condition, or otherwise to improve the health of the subject. The invention also provides methods for determining the effect of a food or food substance on the expression of disease-related genes. The invention further provides methods for modifying the amount of nutraceuticals in raw and processed foods or food substances.