| 摘要 |
A guidewire (10) comprises a core wire (12) having a coil tip at its distal end. The coil tip includes a helically wound filament (28) having adjacent turns spaced apart by a preselected distance. The guidewire (10) is coated with a polymeric material (54), typically a hydrophilic polysaccharide, such as hyaluronic acid or chondroitin sulphate. By properly selecting the spacing between adjacent turns of the coil tip (16), the hydrophilic coating (54) will adhere to the coil tip (16) in a manner which does not penetrate the coil and which does not significantly interfere with flexibility and bend ability of the coil tip.
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