发明名称 |
ENTERIC COATED DILTIAZEM ONCE-A-DAY FORMULATION |
摘要 |
A once-a-day diltiazem dosage form which comprises: (a) a core element which is a compressed tablet which contains a therapeutic dose of diltiazem and an amount of a solubility modulating substance that controls the release of said diltiazem in order to provide a therapeutic level over a period of about 24 hours; and (b) on the outer surface of the core element, a sufficient amount of an enteric coating that causes the diltiazem to release at a rate that permits the use of once-a-day dosing to maintain steady state therapeutic levels of diltiazem.
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申请公布号 |
WO9748386(A1) |
申请公布日期 |
1997.12.24 |
申请号 |
WO1997US09767 |
申请日期 |
1997.06.10 |
申请人 |
ANDRX PHARMACEUTICALS, INC. |
发明人 |
CHEN, CHIH-MING |
分类号 |
A61K9/20;A61K9/28;A61K9/32;A61K9/36;A61K9/48;A61K9/52;A61K31/554;(IPC1-7):A61K9/32;A61K9/34 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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