发明名称 PEPTIDES
摘要 The invention provides novel .beta.-peptides comprising 2 or more different .beta.-amino acid residues, preferably compounds of formula (I) wherein the R residues, X and n are as defined. Compounds of the invention having as few as 5 or 6 .beta.-amino acid residues exhibit stable structures in solution and the compounds generally exhibit good resistance to proteolytic degradation. The compounds of the invention provide a valuable new source of structural diversity for synthesis of biologically active compounds, e.g. for pharmaceutical uses.
申请公布号 CA2256516(A1) 申请公布日期 1997.12.18
申请号 CA19972256516 申请日期 1997.06.12
申请人 NOVARTIS AG 发明人 SEEBACH, DIETER
分类号 A61K31/16;A61K31/325;A61K31/435;C07B61/00;C07C237/22;C07C271/22;(IPC1-7):C07C271/22;C07K7/02;C07K5/023;A61K38/03;C07C279/14;C07D207/16;A61K31/195;C07D209/20;A61K31/215;A61K31/27;A61K31/33;A61K31/40;A61K31/415;C07C323/59;C07D233/64 主分类号 A61K31/16
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