| 摘要 |
<p>Changes in tumor cell RNA and DNA are utilized to detect the progression and the temporal changes in resistance to chemotherapy in human tumors. The present invention provides a method for determining whether human cancer cells are sensitive or resistant to a particular drug, to allow for early detection of drug resistance in order to improve significantly the efficiency of a cancer chemotherapy protocol. The method involves the detection of DNA sequences indicative of drug resistance.</p> |
