A method for enhancing the expression of a selected gene in an organism while avoiding or reducing co-suppression involves the synthesis of a DNA which is altered in nucleotide sequence and is capable of expression of a protein, ideally identical to that of a protein already expressed by a DNA already present in the organism. This method ensures that sequence similarity between the two genes is reduced enough to eliminate the phenomenon of co-suppression, allowing the over-expression of a specific protein. The method is particularly suitable in plants.
申请公布号
WO9746690(A1)
申请公布日期
1997.12.11
申请号
WO1997GB01414
申请日期
1997.05.23
申请人
ZENECA LIMITED;DRAKE, CAROLINE, RACHEL;BIRD, COLIN, ROGER;SCHUCH, WOLFGANG, WALTER
发明人
DRAKE, CAROLINE, RACHEL;BIRD, COLIN, ROGER;SCHUCH, WOLFGANG, WALTER