| 摘要 |
PCT No. PCT/JP95/00211 Sec. 371 Date Jul. 8, 1996 Sec. 102(e) Date Jul. 8, 1996 PCT Filed Feb. 15, 1995 PCT Pub. No. WO95/22533 PCT Pub. Date Aug. 24, 1995A process for the preparation of 3-isoxazolecarboxlic acid which is an intermediate for prepearing useful compounds is provided, said process being characterized in that a compound of formula (I) is reacted with hydroxylamine to obtain a compound of formula (II), and the compound thus obtained is treated with an alkali: <IMAGE> (I) <IMAGE> (II) wherein R1 is a lower alkyl, R2 is a carboxy protecting group, X is a halogen atom, and Y is a hydrogen atom, or X and Y together may form a single bond.
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