发明名称 HETEROCYCLECARBONYL AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS.
摘要 <p>Selected heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide compounds of formula (I) are effective as retroviral protease inhibitors, and in particular as inhibitor of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and the treatment of a retroviral infection.</p>
申请公布号 MX9706946(A) 申请公布日期 1997.11.29
申请号 MX19970006946 申请日期 1996.03.07
申请人 G.D. SEARLE & CO. 发明人 DANIEL P. GETMAN;GARY A. DECRESCENZO;JOHN N. FRESKOS;MICHAEL L. VAZQUEZ;JAMES A. SIKORSKI;BALEKUDRU DEVADAS;SRINIVASAN NAGARAJAN;DAVID L. BROWN;JOSEPH J. MCDONALD
分类号 A61K38/55;A61K31/18;A61K38/00;A61P3/00;A61P31/12;A61P31/18;C07D215/48;C07K5/062;C07K5/078;(IPC1-7):C07K05/078 主分类号 A61K38/55
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