发明名称 A CONTROLLED RELEASE FORMULATION FOR POORLY SOLUBLE BASIC DRUGS.
摘要 <p>A controlled release, oral, solid, pharmaceutical composition for a reduced daily dosage regimen is described where the therapeutic ingredient is a poorly soluble basic drug. The formulation comprises the use of a water-soluble alginate salt, a complex salt of alginic acid and an organic carboxylic acid in admixture with the therapeutic drug. A particular embodiment comprising a once a day dosage form for clarithromycin is also described.</p>
申请公布号 MX9706031(A) 申请公布日期 1997.11.29
申请号 MX19970006031 申请日期 1996.11.25
申请人 ABBOTT LABORATORIES 发明人 NEVILLE A. BOARD;ALAN F. CARMODY;LIAM C. FEEL;BRIAN C. WITHERS
分类号 A61K9/20;A61K9/22;A61K31/165;A61K31/4045;A61K31/4164;A61K31/5513;A61K47/12;A61K47/36;(IPC1-7):A61K09/20 主分类号 A61K9/20
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