| 发明名称 |
DNA-BINDING INDOLE DERIVATIVES, THEIR PRODRUGS AND IMMUNOCONJUGATES AS ANTICANCER AGENTS |
| 摘要 |
The present invention relates to novel DNA alkylating agents and the prodrugs of these agents which are useful as antitumor agents and DNA labelling agents. The compounds are hydroxy dihydrobenzindole oligopeptides and prodrugs thereof wherein the monomeric constituents are derived from monocyclic or bicyclic heterocyclic aromatic residues. |
| 申请公布号 |
WO9744000(A2) |
申请公布日期 |
1997.11.27 |
| 申请号 |
WO1997US09055 |
申请日期 |
1997.05.22 |
| 申请人 |
PANORAMA RESEARCH, INC. |
发明人 |
WANG, YUQIANG;WRIGHT, SUSAN, C.;LARRICK, JAMES, W. |
| 分类号 |
C12P21/08;A61K31/00;A61K31/40;A61K31/403;A61K31/404;A61K31/407;A61K31/415;A61K31/4164;A61K31/4188;A61K31/545;A61K31/546;A61K31/70;A61K31/7028;A61K31/7042;A61K31/7052;A61K31/7056;A61P35/00;C07D209/60;C07D403/06;C07D403/14;C07D405/14;C07D487/04;C07D495/04;C07D501/00;C07D501/22;C07D501/34;C07H15/04;C07H15/24;C07K16/30 |
主分类号 |
C12P21/08 |
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