Benzothiophenes, formulations containing same, and methods

摘要

This invention provides compounds of formula I wherein R<1> is hydrogen, hydroxy, C1-C4 alkoxy, -OCOO(C1-C6 alkyl), -OCO(C1-C6 alkyl), -OCOAr wherein Ar is phenyl or optionally substituted phenyl, -OSO2(C4-C6 straight chain alkyl), or -OSO3H; R<2> is R<1>, Cl or F; with the proviso that at least one of R<1> or R<2> is -OSO3H; R<3> is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-l-pyrrolidino, 4-morpholino, dimethylamino, diethylamino, diisopropylamino, or 1-hexamethyleneimino; and n is 2 or 3; or a pharmaceutically acceptable salt or solvate thereof.