| 发明名称 |
Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors |
| 摘要 |
The invention encompasses the novel compound of Formula I as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. <IMAGE> The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.
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| 申请公布号 |
US5691374(A) |
申请公布日期 |
1997.11.25 |
| 申请号 |
US19950443620 |
申请日期 |
1995.05.18 |
| 申请人 |
MERCK FROSST CANADA INC. |
发明人 |
BLACK, CAMERON;GRIMM, ERICH;WANG, ZHAOYIN;LEGER, SERGE |
| 分类号 |
C07D333/02;A61K31/19;A61K31/365;A61K31/38;A61K31/381;A61P1/00;A61P7/02;A61P13/02;A61P15/00;A61P25/04;A61P29/00;A61P35/02;A61P43/00;C07C317/44;C07C317/46;C07D307/60;C07D307/64;C07D333/52;C07D405/04;C07D407/04;C07D409/04;C07D417/04;(IPC1-7):A61K31/365 |
主分类号 |
C07D333/02 |
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