GENE THERAPY FOR MITOCHONDRIAL DNA DEFECTS USING PEPTIDE NUCLEIC ACIDS
摘要
The invention concerns a method for selectively preventing the replication of mitochondrial DNA using complementary peptide nucleic acids; and the peptide nucleic acids for use in the method. Additionally novel targeting means are described for ensuring the targeting of the peptide nucleic acids into mitochondria.
申请公布号
WO9741150(A2)
申请公布日期
1997.11.06
申请号
WO1997GB01102
申请日期
1997.04.22
申请人
THE UNIVERSITY OF NEWCASTLE UPON TYNE;TURNBULL, DOUGLAS, MATTHEW,;LIGHTOWLERS, ROBERT, NEIL,;TAYLOR, ROBERT, WILLIAM,