发明名称 |
Peptide determinant associated with immunity |
摘要 |
<p>Novel peptides are provided involving sequences from proteins of interest which include a motif comprising a charged amino acid, followed by two hydrophobic amino acids, followed in the next or succeeding position by a polar amino acid, where the charged or polar amino acid may be substituted by glycine. Peptides having the motif are found to be stimulatory to T-cells and allow for modulation of immune response, as illustrated by tolerizing the host to neurological proteins.</p> |
申请公布号 |
EP0805162(A1) |
申请公布日期 |
1997.11.05 |
申请号 |
EP19970106788 |
申请日期 |
1988.08.17 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
STEINMAN, LAWRENCE;ZAMVIL, SCOTT |
分类号 |
A61K38/00;A61K39/00;A61P35/00;A61P37/00;C07K14/47;C07K14/705;A61K35/14;(IPC1-7):C07K14/47;A61K38/17 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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