| 发明名称 |
GABA and L-glutamic acid analogs for antiseizure treatment |
| 摘要 |
A compound of the formula <IMAGE> I wherein R1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R2 is hydrogen or methyl; and R3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.
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| 申请公布号 |
US5684189(A) |
申请公布日期 |
1997.11.04 |
| 申请号 |
US19950420576 |
申请日期 |
1995.04.12 |
| 申请人 |
NORTHWESTERN UNIVERSITY;WARNER-LAMBERT COMPANY |
发明人 |
SILVERMAN, RICHARD B.;ANDRUSZKIEWICZ, RYSZARD;YUEN, PO-WAI;SOBIERAY, DENIS MARTIN;FRANKLIN, LLOYD CHARLES;SCHWINDT, MARK ALAN |
| 分类号 |
A61K31/197;C07C69/34;C07C69/675;C07C229/08;C07C229/24;C07C229/28;C07C229/34;C07C247/12;C07C309/73;C07D263/22;C07D263/26;G11B20/14;G11B27/30;(IPC1-7):C07C205/00 |
主分类号 |
A61K31/197 |
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