| 摘要 |
The invention provides methods and compositions relating to a novel tumor necrosis factor receptor associated factor number six (TRAF6) polypeptide, which transcriptionally activates Nuclear Factor kappa B. The invention provides isolated TRAF6 hybridization probes and primers capable of hybridizing with the disclosed TRAF6 gene, nucleic acids encoding the subject TRAF6 polypeptides, methods of making the subject TRAF6 polypeptides, and methods of using the subject compositions in diagnosis and drug screening.
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