发明名称 SESQUITERPENE-BASED COMPOUND
摘要 PROBLEM TO BE SOLVED: To obtain a sesquiterpene-based compound useful as a raw material for a medicine, especially an antibacterial agent or an antifungal agent. SOLUTION: This sesquiterpene-based compound is shown by formula I (R is H, ammonium, an alkali metal or a lower alkyl) or formula II. The compound is obtained by finely cutting the fruit body of Roseofomes subflexibilis Aoshi as a mushroom of the family Polyporaceae, immersing the fruit body in acetone, ethyl acetate or a lower alcohol at room temperature for 1-3 days to give an extracted essence, concentrating the essence under reduced pressured suspending a viscous residue in water, extracting the suspension with ethyl acetate and purifying the extract by silica gel chromatography, preparative thin-layer chromatography, high-performance liquid chromatography, etc.
申请公布号 JPH09278708(A) 申请公布日期 1997.10.28
申请号 JP19960116985 申请日期 1996.04.15
申请人 TOAGOSEI CO LTD 发明人 NOZOE SHIGEO;TAKAHASHI AKIRA;MASUDA JUNICHI;TANAKA KENICHI;TANAKA SANAE;KANO MUNEAKI;SEGAWA TOSHIAKI
分类号 C07D307/92;A61K31/19;A61K31/365;A61K36/07;A61P31/04;A61P31/10;C07C62/36;C07C69/757 主分类号 C07D307/92
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