| 摘要 |
Imidazo benzoxazine derivatives of formula (I), their pure and mixed enantiomers, including racemic mixtures and acid addition salts are new. R1, R2 = H, alkyl, alkenyl, cycloalkyl, cycloalkenyl, or alkylene-cycloalkyl; or R1+R2 = cycloalkyl; R3 = H, halo, nitro, amino, alkylamino, dialkylamino, acylamino, cyano, carboxamide, -COOH, amino-methylene, amidino, alkyl, fluoroalkyl, aralkylamino, -SO2NR5R6 or -NR7SO2R8; R5-R8 = H or alkyl; R4 = H, alkyl, alkenyl, cycloalkyl, cycloalkenyl, aralkyl, alkoxyalkyl, fluoroalkyl, phenoxyalkyl, -(CH2)m-NR9SO2R10, -(CH2)z-SO2NR11R12 or -(CH2)v-CONR13R14; m, v, z = 2 or 3; R9-R14 = H, alkyl, alkenyl, cycloalkyl or cycloalkenyl; Y = O, NH, N-alkyl or S; n = 0-2.
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