| 摘要 |
The invention concerns quinazoline derivatives of formula (I) wherein n is 1, 2 or 3 and each R<2> is independently halogeno, trifluoromethyl or (1-4C)alkyl; R<1> is (1-4C)alkoxy; A is (1-4C)alkylene; and Q is a saturated, monocyclic 4-, 5-, 6- or 7-membered heterocyclic ring containing one or two oxygen heteroatoms, which ring optionally bears up to four (1-4C)alkyl substituents; or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and the use of their receptor tyrosine kinase inhibitory properties in the treatment of proliferative disease such as cancer.
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