发明名称 |
GENOMIC NUCLEIC ACIDS, cDNA AND mRNA WHICH CODE FOR POLYPEPTIDES WITH IL-16 ACTIVITY, PROCESSES FOR THE PRODUCTION THEREOF AND THEIR USE |
摘要 |
A nucleic acid with which expression of a polypeptide having interleukin-16 activity can be achieved or regulated in a prokaryotic or eukaryotic host cell, wherein in the region coding for the said polypeptide said nucleic acid (a) corresponds to the DNA sequence SEQ ID NO:1 or its complementary strand; (b) hybridizes under stringent conditions with the DNA of sequence SEQ ID NO:1; (c) or is a nucleic acid sequence which, if there was no degeneracy of the genetic code, would hybridize under stringent conditions with the nucleic acid sequences defined by (a) and (b); (d) and, if it codes for a polypeptide having interleukin-16 activity, has a length of at least 1179 coding nucleotides, is suitable as genomic DNA for the recombinant production of IL-16 in eukaryotic host cells.
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申请公布号 |
WO9738105(A1) |
申请公布日期 |
1997.10.16 |
申请号 |
WO1997EP01753 |
申请日期 |
1997.04.09 |
申请人 |
BUNDESREPUBLIK DEUTSCHLAND VERTRETEN DURCH DEN BUN;KURTH, REINHARD;BAIER, MICHAEL;BANNERT, NORBERT;METZNER, KARIN;WERNER, ALBRECHT |
发明人 |
KURTH, REINHARD;BAIER, MICHAEL;BANNERT, NORBERT;METZNER, KARIN;WERNER, ALBRECHT |
分类号 |
C12N15/09;A61K38/00;A61K38/20;A61P31/12;A61P31/18;A61P43/00;C07K14/54;C12N5/10;C12N15/24;C12P21/02;(IPC1-7):C12N15/24 |
主分类号 |
C12N15/09 |
代理机构 |
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地址 |
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