| 发明名称 |
Vaccine against varicella-zoster virus |
| 摘要 |
<p>A gene of varicella-zoster virus (VZV) which encodes immunogenic outer surface viral proteins has been identified by DNA sequence analysis. This gene can hybrid select messenger RNA which encodes and expresses a protein which reacts with human convalescent zoster sera and with polyclonal monospecific antisera which neutralize viral infectivity. These proteins are useful for the preparation of a vaccine for VZV.</p> |
| 申请公布号 |
EP0482671(B1) |
申请公布日期 |
1997.10.15 |
| 申请号 |
EP19910120701 |
申请日期 |
1986.07.31 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
ELLIS, RONALD W.;LOWE, ROBERT S.;KELLER, PAUL M.;DAVISON, ANDREW J. |
| 分类号 |
C12N15/09;A61K39/00;A61K39/25;C07H21/04;C07K14/00;C07K14/04;C12N1/00;C12N5/00;C12N5/10;C12N15/00;C12N15/38;C12P21/02;C12R1/125;C12R1/19;C12R1/865;C12R1/91;(IPC1-7):C12N15/38 |
主分类号 |
C12N15/09 |
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