| 摘要 |
Amidino and benzamidino compounds, including compounds of formula (I), wherein R<1>-R<4>, R<6>-R<9>, Y, Z, n and m are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof, that inhibit proteolytic enzymes such as thrombin are described. Also described are methods for preparing the compounds of formula (I).
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| 申请人 |
3-DIMENSIONAL PHARMACEUTICALS, INC.;SOLL, RICHARD, M.;LU, TIANBAO;FEDDE, CYNTHIA, L.;TOMCZUK, BRUCE, E.;ILLIG, CARL |
发明人 |
SOLL, RICHARD, M.;LU, TIANBAO;FEDDE, CYNTHIA, L.;TOMCZUK, BRUCE, E.;ILLIG, CARL |
