发明名称 |
Catalytic antibodies and a method of producing same |
摘要 |
The present invention relates generally to a growth factor precursor and its use to select production of antigen specific catalytic antibodies. Such catalytic antibodies are produced following B cell activation and proliferation induced by catalytic cleavage products of a target antigen portion of the growth factor precursor of the present invention. A particularly useful form of the growth factor precursor is as a nucleic acid vaccine. The nucleic acid vaccine of the present invention preferably further comprises a molecular adjuvant. Another aspect of the present invention comprises a growth factor precursor in multimeric form. The growth factor precursor of the present invention is useful for generating catalytic antibodies for both therapeutic, diagnostic and industrial purposes. |
申请公布号 |
AUPO930697(D0) |
申请公布日期 |
1997.10.09 |
申请号 |
AU1997PO09306 |
申请日期 |
1997.09.19 |
申请人 |
WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH, THE |
发明人 |
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分类号 |
C07K16/18;C12N9/00;C12N15/19 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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