| 摘要 |
<p>A polypeptide that has the amino acid sequence represented by SEQ ID NO:1 or that has an amino acid sequence resulting from amino acid deletion, substitution or addition in the above amino acid sequence and has a cell proliferation inhibitory activity; a DNA encoding the polypeptide; a DNA that has a base sequence represented by SEQ ID NO:1 or 2, or that hybridizes with an oligonucleotide probe prepared on the basis of the above base sequence; a recombinant vector comprising the DNA; a transformant prepared by introducing the vector into host cells; a process for producing the polypeptide by culturing the transformant in a medium; medicines containing the polypeptide as the active ingredient, preferably antitumor agents; a method of preventing or curing tumors by administering the polypeptide in an efficacious quantity; and the use of the polypeptide for producing pharmacological compositions efficacious in tumor prevention or curing.</p> |
